AMP2010

Sunday, 8 August 2010
16:00 – 19:00     Registration (at MedILS)
19:00 – 20:00     Reception and refreshments
20:00 – 20:30     Welcome and introduction (Miroslav Radman, Davor Juretić and Frances Separovic)
20:30 – 21:00     Poster placement


Monday, 9 August 2010
Computer modelling studies (Chair: Luca Marsella, Bono Lučić)
8:30 – 9:25        Alan Mark, University of Queensland, Brisbane, Australia
Antimicrobial peptide insertion and assembly - insights from atomistic simulations

9:30 – 10:20      David Smith, Ruđer Bošković Institute, Zagreb
Replica-exchange molecular dynamics studies on natural and non-natural opioid peptides

10:20 – 10:50    Coffee break

10:50 – 11:45    Nevena Todorova, RMIT University, Melbourne, Australia
Simulation of the effects of environment on peptide dynamics

11:45 – 13:00    Poster session I

13:00 – 15:00    Lunch break

15:00-15:55     Bojan Žagrović, Max F. Perutz Laboratories & University of Vienna, Vienna, Austria
Computational biophysics of macromolecules: protein-protein interactions in a crowded cell

15:55-16:50      Vlasta Bonačić-Koutecký, Humboldt-University Berlin, Berlin, Germany
Optical properties of noble metal cluster-chromophores interacting with biomolecules

16:50 – 17:20    Coffee break

17:20 – 19:20    Tutorial – Part I (David Smith, Alan Mark and Luca Marsella)


Tuesday, 10 August 2010

NMR methods and drug design (Chair: Renato Gennaro)

8:30-9:25            David Craik, The University of Queensland, Brisbane, Australia
NMR and protein structure in drug design

9:25-10:20         Frances Separovic, University of Melbourne, Melbourne, Australia
NMR studies of antimicrobial peptides in model membranes

10:20-10:50       Coffee break

Mechanism of action: DPI and QCM analysis (Chair: Alan Mark)

10:50-11:45      Mibel Aguilar, Monash University, Melbourne, Australia
Profiling of membrane structure changes during the adsorption, destabilisation and lysis of antimicrobial peptides using optical biosensors

11:45- 12:40     Lisa Martin, Monash University, Melbourne, Australia
Interrogation of antimicrobial peptide activity at membranes: a quartz crystal microbalance approach

12:40- 14:30      Lunch break

14:30 – 15:45    Tutorial - Part II (David Craik)

15:45 – 17:00    Tutorial - Part III (Frances Separovic)

17:30 – 20:00     City tour


Wednesday, 11 August 2010
Antimicrobial peptides: Structure, Activity and Design (Chair: Nedia Kamech)

8:30-9:25           Damir Vukičević, University of Split, Split
Designer algorithm

9:25-10:20       Davor Juretić, University of Split, Split
Computational methods for using known antimicrobial peptide sequences to identify or design novel non-homologous peptides

10:20-10:50       Coffee break

10:50-11:45       Renato Gennaro, University of Trieste, Trieste, Italy
Breach or passage – differential modes of action at the bacterial membrane for   helical and proline-rich cathelicidin AMPs

12:00 -               Excursion (to Cetina river with organized lunch and
return to Split at 18:00 or 22:00)


Thursday, 12 August
Antimicrobial peptides – synthetic analogues (Chair: Mibel Aguilar)

8:30-9:25           Akhter Hossain, University of Melbourne, Melbourne, Australia
Modern solid-state peptide synthesis: Application to antimicrobial peptides

Contributed talks:
9:25-9:50         Tatjana Heinrich, Telethon Institute for Child Health Research, Perth, Australia
Isolation of antimicrobial peptides from a T7-phylomer® peptide display library

9:50-10:15        Amy Won, Carleton University, Ottawa, Canada
Effect of single and multiple amino acid substitutions on the membrane binding and lytic activity of antimicrobial peptide Anoplin

10:15-10:45      Coffee break

Antimicrobial peptides from flowering plants (Chair: Eva Kondorosi)
Contributed talks:
10:45-11:10       Gergely Maroti, BayGen Institute, Szeged, Hungary
Nodule specific Madicago peptides exhibit strong antibacterial activity

11:10-11:35      Christian Gruber, University of Vienna, Vienna, Austria
Discovery and distribution of circular peptides in flowering plants 

11:35-12:00      Sonia Troeira Henriques, University of Queensland, Brisbane, Australia
The bioactivity of cyclotides is dependent on their affinity for the lipid bilayer

12:00–15:00      Lunch break and beachside discussions

15:00-16:15       Poster session II

16:15 –17:45     Tutorial – Part IV  (Alan Mark, David Smith and Luca Marsella)

17:45-18:45       Collaboration session I

19:30 -                Conference dinner


Friday, 13 August
(Chair: Davor Juretić)
9:00 - 9:55          Ante Graovac, Ruđer Bošković Institute, Zagreb
Topological coordinates for carbon nanostructures

9:55 –11:10        Poster awards + Selected talks by PhD students

11:10-11:40        Coffee break

11:40 –12:55      Tutorial Part V (Lisa Martin and Slavica Praporski)

12:55 –15:00       Lunch break

15:00 – 17:00      Tutorial part VI (David Smith and Luca Marsella)
17:00 – 18:00      Collaboration session II
18:00 –18:30       Wrap up


Saturday, 14 August

Travelling home