Principal organizer:
Professor Davor Juretić
Physics Department, Faculty of Science,
University of Split, Nikole Tesle 12, 21000 Split, Croatia
Phone: +385 21 385 133
Fax: +385 21 385 431

Australian co-organizer:
Professor Frances Separovic
School of Chemistry, Bio21 Institute
University of Melbourne, VIC 3010, Australia
Phone: +61 3 8344 7137
Fax: +61 3 9347 5180


PostHeaderIcon Workshop Program

Sunday, 8 August 2010
16:00 – 19:00     Registration (at MedILS)
19:00 – 20:00     Reception and refreshments
20:00 – 20:30     Welcome and introduction (Miroslav Radman, Davor Juretić and Frances Separovic)
20:30 – 21:00     Poster placement

Monday, 9 August 2010
Computer modelling studies (Chair: Luca Marsella, Bono Lučić)
8:30 – 9:25        Alan Mark, University of Queensland, Brisbane, Australia
Antimicrobial peptide insertion and assembly - insights from atomistic simulations

9:30 – 10:20      David Smith, Ruđer Bošković Institute, Zagreb
Replica-exchange molecular dynamics studies on natural and non-natural opioid peptides

10:20 – 10:50    Coffee break

10:50 – 11:45    Nevena Todorova, RMIT University, Melbourne, Australia
Simulation of the effects of environment on peptide dynamics

11:45 – 13:00    Poster session I

13:00 – 15:00    Lunch break

15:00-15:55     Bojan Žagrović, Max F. Perutz Laboratories & University of Vienna, Vienna, Austria
Computational biophysics of macromolecules: protein-protein interactions in a crowded cell

15:55-16:50      Vlasta Bonačić-Koutecký, Humboldt-University Berlin, Berlin, Germany
Optical properties of noble metal cluster-chromophores interacting with biomolecules

16:50 – 17:20    Coffee break

17:20 – 19:20    Tutorial – Part I (David Smith, Alan Mark and Luca Marsella)

Tuesday, 10 August 2010

NMR methods and drug design (Chair: Renato Gennaro)

8:30-9:25            David Craik, The University of Queensland, Brisbane, Australia
NMR and protein structure in drug design

9:25-10:20         Frances Separovic, University of Melbourne, Melbourne, Australia
NMR studies of antimicrobial peptides in model membranes

10:20-10:50       Coffee break

Mechanism of action: DPI and QCM analysis (Chair: Alan Mark)

10:50-11:45      Mibel Aguilar, Monash University, Melbourne, Australia
Profiling of membrane structure changes during the adsorption, destabilisation and lysis of antimicrobial peptides using optical biosensors

11:45- 12:40     Lisa Martin, Monash University, Melbourne, Australia
Interrogation of antimicrobial peptide activity at membranes: a quartz crystal microbalance approach

12:40- 14:30      Lunch break

14:30 – 15:45    Tutorial - Part II (David Craik)

15:45 – 17:00    Tutorial - Part III (Frances Separovic)

17:30 – 20:00     City tour

Wednesday, 11 August 2010
Antimicrobial peptides: Structure, Activity and Design (Chair: Nedia Kamech)

8:30-9:25           Damir Vukičević, University of Split, Split
Designer algorithm

9:25-10:20       Davor Juretić, University of Split, Split
Computational methods for using known antimicrobial peptide sequences to identify or design novel non-homologous peptides

10:20-10:50       Coffee break

10:50-11:45       Renato Gennaro, University of Trieste, Trieste, Italy
Breach or passage – differential modes of action at the bacterial membrane for   helical and proline-rich cathelicidin AMPs

12:00 -               Excursion (to Cetina river with organized lunch and
return to Split at 18:00 or 22:00)

Thursday, 12 August
Antimicrobial peptides – synthetic analogues (Chair: Mibel Aguilar)

8:30-9:25           Akhter Hossain, University of Melbourne, Melbourne, Australia
Modern solid-state peptide synthesis: Application to antimicrobial peptides

Contributed talks:
9:25-9:50         Tatjana Heinrich, Telethon Institute for Child Health Research, Perth, Australia
Isolation of antimicrobial peptides from a T7-phylomer® peptide display library

9:50-10:15        Amy Won, Carleton University, Ottawa, Canada
Effect of single and multiple amino acid substitutions on the membrane binding and lytic activity of antimicrobial peptide Anoplin

10:15-10:45      Coffee break

Antimicrobial peptides from flowering plants (Chair: Eva Kondorosi)
Contributed talks:
10:45-11:10       Gergely Maroti, BayGen Institute, Szeged, Hungary
Nodule specific Madicago peptides exhibit strong antibacterial activity

11:10-11:35      Christian Gruber, University of Vienna, Vienna, Austria
Discovery and distribution of circular peptides in flowering plants 

11:35-12:00      Sonia Troeira Henriques, University of Queensland, Brisbane, Australia
The bioactivity of cyclotides is dependent on their affinity for the lipid bilayer

12:00–15:00      Lunch break and beachside discussions

15:00-16:15       Poster session II

16:15 –17:45     Tutorial – Part IV  (Alan Mark, David Smith and Luca Marsella)

17:45-18:45       Collaboration session I

19:30 -                Conference dinner

Friday, 13 August
(Chair: Davor Juretić)
9:00 - 9:55          Ante Graovac, Ruđer Bošković Institute, Zagreb
Topological coordinates for carbon nanostructures

9:55 –11:10        Poster awards + Selected talks by PhD students

11:10-11:40        Coffee break

11:40 –12:55      Tutorial Part V (Lisa Martin and Slavica Praporski)

12:55 –15:00       Lunch break

15:00 – 17:00      Tutorial part VI (David Smith and Luca Marsella)
17:00 – 18:00      Collaboration session II
18:00 –18:30       Wrap up

Saturday, 14 August

Travelling home

Travel Information

Medils and PMF

Please apply directly to EBSA Bursaries for support




An earlier version of conference announcement (September 17th, 2009) can be found at the official MedILS web page: