PYLa/PGLa B

Entry PYLa/PGLa B
Uniprot code Q91826
Fasta Q91826
Peptide names PYLa/PGLa B PYLa PGLa H PGLa-H
Suborder Mesobatrachia
Family Pipidae
Genus Xenopus
Species Xenopus laevis
Ecozone Afrotropic
Distribution Extreme southern Angola south to Cape Region of Rep. South Africa thence east and north in savanna habitats to north-east-central Central African Republic and southern Sudan and then west to Nigeria; introduced in southern California, Arizona, USA, Mexico, Chile, France, Mexico, Italy, and Java, Indonesia, as well as Ascension Island
Antimicrobial & other activities antibacterial
Tissue Skin
Sequence MYKQIFLCLIIAALCATIMAEASALADADDDDDKRYVRGMASKAGAIAGKIAKVALKALG
RRDS
Length 64
Signal peptide class Class-4
References:
1. for MIC/HC50 F. Hou et al. / International Journal of Antimicrobial Agents 38 (2011) 510-515. Isolation and characterisation of a new antimicrobial peptide from the skin of Xenopus laevis


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   20   MYKQIFLCLIIAALCATIMA    
Prepro15 EASALADADDDDDKR   
BioactivePYLa24NoYVRGMASKAGAIAGKIAKVALKAL   
BioactivePGLa21NoGMASKAGAIAGKIAKVALKAL   
BioactivePGLa-H10NoKIAKVALKAL 22.48.3