Dermaseptin DRG1

Entry Dermaseptin DRG1
Uniprot code Q90ZK3
Fasta Q90ZK3
Peptide names Dermaseptin DRG1
Suborder Neobatrachia
Family Hylidae
Genus Phyllomedusa
Species Phyllomedusa bicolor
Ecozone Neotropic
Distribution Amazon Basin in Brazil, Colombia, Bolivia, and Peru; the Guianan region of Venezuela and the Guianas. Possibly to be found in eastern Ecuador
Antimicrobial & other activities antibacterial
Tissue Skin
Sequence MASLKKSLFLVLFLGLVSLSICEEEKRENEDEEEQEDDEQSEMKRGLWSNIKTAGKEAAK
AALKAAGKAALGAVTDAVGEQ
Length 81
Signal peptide class Class-1


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MASLKKSLFLVLFLGLVSLSIC    
Prepro23 EEEKRENEDEEEQEDDEQSEMKR   
BioactiveDermaseptin DRG133NoGLWSNIKTAGKEAAKAALKAAGKAALGAVTDAV