Ranatuerin-2P

Entry Ranatuerin-2P
Uniprot code Q8QFQ4
Fasta Q8QFQ4
Peptide names Ranatuerin-2P
Suborder Neobatrachia
Family Ranidae
Genus Lithobates
Species Lithobates pipiens
Ecozone Nearctic
Distribution Southern Canada (southeastern British Columbia to southern Northern Territory east to Labrador and Nova Scotia) south through eastern Washington eastern Oregon, Nevada and adjacent California to northern Arizona, northern New Mexico (with islolated populations along the Rio Grande south to Las Cruces), thence east-northeast to central Nebraska, Ohio, northern Kentucky, West Virginia, and New England, USA
Antimicrobial & other activities antibacterial, antifungal
Tissue Skin
Sequence MFTMKKSLLLFFFLGTISLSLCEQERGADEDDGVEITEEEVKRGLMDTVKNVAKNLAGHM
LDKLKCKITGC
Length 71
Signal peptide class Class-1
References:
1. for MIC/HC50 J. Goraya et al. / Eur. J. Biochem. 267 (2000) 894-900. Peptides with antimicrobial activity from four different families isolated from the skins of the North American frogs Rana luteiventris, Rana berlandieri and Rana pipiens


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFTMKKSLLLFFFLGTISLSLC    
Prepro21 EQERGADEDDGVEITEEEVKR   
BioactiveRanatuerin-2P28NoGLMDTVKNVAKNLAGHMLDKLKCKITGC 1350