Dermaseptin-like PBN2

Entry Dermaseptin-like PBN2
Uniprot code Q800R4
Fasta Q800R4
Peptide names Dermaseptin-like PBN2 Plasticin-B1 PTC-B1 DRP-PBN2
Suborder Neobatrachia
Family Hylidae
Genus Phyllomedusa
Species Phyllomedusa bicolor
Ecozone Neotropic
Distribution Amazon Basin in Brazil, Colombia, Bolivia, and Peru; the Guianan region of Venezuela and the Guianas. Possibly to be found in eastern Ecuador
Antimicrobial & other activities antibacterial, antifungal, anticancer
Tissue Skin
Sequence MAFLKKSLFLVLFLALVPLSICEEKKSEEENEEKQEDDQSEEKRGLVTSLIKGAGKLLGG
LFGSVTGGQS
Length 70
Signal peptide class Class-1
References:
1. for MIC/HC50 P. Nicolas and C. El Amri / Biochimica et Biophysica Acta 1788 (2009) 1537-1550. The dermaseptin superfamily: a gene-based combinatorial library of antimicrobial peptides


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MAFLKKSLFLVLFLALVPLSIC    
Prepro22 EEKKSEEENEEKQEDDQSEEKR   
BioactiveDermaseptin-like PBN226NoGLVTSLIKGAGKLLGGLFGSVTGGQS 6.256.25