Aurein 2.2

Entry Aurein 2.2
Uniprot code Q5K0E6
Fasta Q5K0E6
Peptide names Aurein 2.2
Suborder Neobatrachia
Family Hylidae
Genus Litoria
Species Litoria aurea
Ecozone Australasia
Distribution Eastern New South Wales, south of the Richmond River, Australia; introduced into New Zealand, New Caledonia, and the New Hebrides Island
Antimicrobial & other activities antibacterial, anticancer, nNOS inhibitor
Tissue Skin
Sequence MAFLKKSLFLVLFLGLVSLSICEKEKRQNEEDEDENEAANHEEGSEEKRGLFDIVKKVVG
ALGSLGKRNDLE
Length 72
Signal peptide class Class-1
References:
2. for other activities M.A. Apponyi et al. / Peptides 25 (2004) 1035-1054. Host-defence peptides of Australian anurans: structure, mechanism of action and evolutionary significance


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MAFLKKSLFLVLFLGLVSLSIC    
Prepro27 EKEKRQNEEDEDENEAANHEEGSEEKR   
BioactiveAurein 2.216YesGLFDIVKKVVGALGSL