Maximin 4/H3 type 2

Entry Maximin 4/H3 type 2
Uniprot code Q58T79
Fasta Q58T79
Peptide names Maximin 4/H3 type 2 Maximin 4 Maximin H3
Suborder Archeobatrachia
Family Bombinatoridae
Genus Bombina
Species Bombina maxima
Ecozone Palearctic, Indomalaya
Distribution Yunnan, southwestern Sichuan, Hubei, Guizhou, and northern Guangxi, China; adjacent northern Vietnam
Antimicrobial & other activities antibacterial, antifungal, anticancer; Maximin H3: antibacterial, antifungal
Tissue Skin
Sequence MNFKYIIAVSFFIASAYARRNEKDVQSLSQRDVLEEESLREIRGIGGVLLSAGKAALKGL
AKVLAEKYANGKRTAEDHEVMKRLEAVMRDLDSLDHPEEASERETRGFNQEEIANLFTKK
EKRILGPVLGLVGNALGGLIKKIG
Length 144
Signal peptide class Class-3
References:
1. for MIC/HC50 R. Lai et al. / Peptides 23 (2002) 427-435. Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   18   MNFKYIIAVSFFIASAYA    
Prepro25 RRNEKDVQSLSQRDVLEEESLREIR   
BioactiveMaximin 427YesGIGGVLLSAGKAALKGLAKVLAEKYAN 1.031.03
Prepro53 GKRTAEDHEVMKRLEAVMRDLDSLDHPEEASERETRGFNQEEIANLFTKKEKR   
BioactiveMaximin H320YesILGPVLGLVGNALGGLIKKI 10.295.15