Maximin 9/H3

Entry Maximin 9/H3
Uniprot code Q58T55
Fasta Q58T55
Peptide names Maximin 9 Maximin H3 Maximin 9/H3
Suborder Archeobatrachia
Family Bombinatoridae
Genus Bombina
Species Bombina maxima
Ecozone Palearctic, Indomalaya
Distribution Yunnan, southwestern Sichuan, Hubei, Guizhou, and northern Guangxi, China; adjacent northern Vietnam
Antimicrobial & other activities antibacterial, antimycoplasma; Maximin H3: antibacterial, antifungal
Tissue Skin
Sequence MNFKYIVAVSFLIASAYARSVKNDEQSLSQRDVLEEESLREIRGIGRKFLGGVKTTFRCG
VKDFASKHLYGKRTAEEHEVMKRLEAIMRDLDSLDHPEEASERETRGFNQDEIANLFTKK
EKRILGPVLGLVGNALGGLIKKIG
Length 144
Signal peptide class Class-3
References:
1. for MIC/HC50 Wen-Hui Lee et al. / FEBS Letters 579 (2005) 4443-4448. Maximin 9, a novel free thiol containing antimicrobial peptide with antimycoplasma activity from frog Bombina maxima; R. Lai et al. / Peptides 23 (2002) 427-435. Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   18   MNFKYIVAVSFLIASAYA    
Prepro25 RSVKNDEQSLSQRDVLEEESLREIR   
BioactiveMaximin 927YesGIGRKFLGGVKTTFRCGVKDFASKHLY 150 
Prepro53 GKRTAEEHEVMKRLEAIMRDLDSLDHPEEASERETRGFNQDEIANLFTKKEKR   
BioactiveMaximin H320YesILGPVLGLVGNALGGLIKKI 10.295.15