Maximin 2/H8 type 1

Entry Maximin 2/H8 type 1
Uniprot code Q58T49
Fasta Q58T49
Peptide names Maximin 2/H8 type 1 Maximin 2 Maximin H8
Suborder Archeobatrachia
Family Bombinatoridae
Genus Bombina
Species Bombina maxima
Ecozone Palearctic, Indomalaya
Distribution Yunnan, southwestern Sichuan, Hubei, Guizhou, and northern Guangxi, China; adjacent northern Vietnam
Antimicrobial & other activities antibacterial, antifungal
Tissue Skin
Sequence MNFKYIVAVSFLIASAYARSEENEIQSLSQRDVLEEESLREMRGIGTKILGGVKTALKGA
LKELASTYVNGKRTAEEHEVMKRLETVMRDLDSLDYPEEASERETRGFNQEEIANLFTKK
EKRILGPVLGLVSNALGGLLKNIG
Length 144
Signal peptide class Class-3
References:
1. for MIC/HC50 R. Lai et al. / Peptides 23 (2002) 427-435. Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   18   MNFKYIVAVSFLIASAYA    
Prepro25 RSEENEIQSLSQRDVLEEESLREMR   
BioactiveMaximin 227YesGIGTKILGGVKTALKGALKELASTYVN 7.227.22
Prepro53 GKRTAEEHEVMKRLETVMRDLDSLDYPEEASERETRGFNQEEIANLFTKKEKR   
BioactiveMaximin H820NoILGPVLGLVSNALGGLLKNI