Frenatin 3

Entry Frenatin 3
Uniprot code Q571V5
Fasta Q571V5
Peptide names Frenatin 3
Suborder Neobatrachia
Family Hylidae
Genus Litoria
Species Litoria infrafrenata
Ecozone Australasia
Distribution Lowlands of New Guinea; extending westwards to the islands of Timor, Halmahera, Seram, Buru, and Talaud Island; eastwards to New Ireland, Bismarck Archipelago, and south to the Aru Islands and Cape York Peninsula, Queensland, Australia; introduced into Java
Antimicrobial & other activities nNOS inhibitor
Tissue Skin
Sequence MHFLKKSIFLVLFLGLVSLSICEKEKREDQNEEEVDENEEESEEKRGLMSVLGHAVGNVL
GGLFKPKS
Length 68
Signal peptide class Class-1
References:
2. for other activities M.A. Apponyi et al. / Peptides 25 (2004) 1035-1054. Host-defence peptides of Australian anurans: structure, mechanism of action and evolutionary significance


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MHFLKKSIFLVLFLGLVSLSIC    
Prepro24 EKEKREDQNEEEVDENEEESEEKR   
BioactiveFrenatin 322NoGLMSVLGHAVGNVLGGLFKPKS