Esculentin-1P

Entry Esculentin-1P
Uniprot code Q1MU23
Fasta Q1MU23
Peptide names Esculentin-1P Esculentin-1A
Suborder Neobatrachia
Family Ranidae
Genus Pelophylax
Species Pelophylax fukienensis
Ecozone Indomalaya
Distribution Southeastern China (Jianxi, Fujian) and Taiwan
Antimicrobial & other activities antibacterial
Tissue Skin
Sequence MFTLKKPLLLIVLLGMISLSLCEQKRDDDEEEGSETKRGIFSKLAGKKIKNLLISGLKNV
GKEVGMDVVRTGIDIAGCKIKGEC
Length 84
Signal peptide class Class-1
References:
1. for MIC/HC50 T. Chen et al. / Genomics 87 (2006) 638-644. Cloning from tissue surrogates: Antimicrobial peptide (esculentin) cDNAs from the defensive skin secretions of Chinese ranid frogs


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFTLKKPLLLIVLLGMISLSLC    
Prepro16 EQKRDDDEEEGSETKR   
BioactiveEsculentin-1P46NoGIFSKLAGKKIKNLLISGLKNVGKEVGMDVVRTGIDIAGCKIKGEC 2.84.3