Esculentin-2P

Entry Esculentin-2P
Uniprot code Q1MU22
Fasta Q1MU22
Peptide names Esculentin-2P
Suborder Neobatrachia
Family Ranidae
Genus Pelophylax
Species Pelophylax fukienensis
Ecozone Indomalaya
Distribution Southeastern China (Jianxi, Fujian) and Taiwan
Antimicrobial & other activities antibacterial
Tissue Skin
Sequence MFTLKKSLLLLFFIGTISLSLCEEERNADEEEGGEVQEEEVKRGIFSLIKGAAKVVAKGL
GKEVGKFGLDLMACKVTNQC
Length 80
Signal peptide class Class-1
References:
1. for MIC/HC50 T. Chen et al. / Genomics 87 (2006) 638-644. Cloning from tissue surrogates: Antimicrobial peptide (esculentin) cDNAs from the defensive skin secretions of Chinese ranid frogs


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFTLKKSLLLLFFIGTISLSLC    
Prepro21 EEERNADEEEGGEVQEEEVKR   
BioactiveEsculentin-2P37NoGIFSLIKGAAKVVAKGLGKEVGKFGLDLMACKVTNQC 0.92.2