Caerin-1.16

Entry Caerin-1.16
Uniprot code P86503
Fasta P86503
Peptide names Caerin-1.16 Caerin 1.6
Suborder Neobatrachia
Family Hylidae
Genus Litoria
Species Litoria rothii
Ecozone Australasia
Distribution Northern Australia from northern Western Australia to Queensland north of Mary River; southern New Guinea between the Bensbach and Binaturi River, all near sea level
Antimicrobial & other activities antibacterial, anticancer, nNOS inhibitor
Tissue Skin
Sequence
Length 25
References:
1. for MIC/HC50 P.A. Wabnitz et al. / European Journal of Biochemistry 267 (2000) 269-275. Differences in the skin peptides of the male and female Australian tree frog Litoria splendida. The discovery of the aquatic male sex pheromone splendipherin, together with phe8 caerulein and a new antibiotic peptide caerin 1.10
2. for other activities M.A. Apponyi et al. / Peptides 25 (2004) 1035-1054. Host-defence peptides of Australian anurans: structure, mechanism of action and evolutionary significance


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
BioactiveCaerin-1.1625YesGLFSVLGAVAKHVLPHVVPVIAEKL 19.272.31