Phylloseptin-7

Entry Phylloseptin-7
Uniprot code P85882
Fasta P85882
Peptide names Phylloseptin-P1 Phylloseptin-7 Phylloseptin 7 PS-7
Suborder Neobatrachia
Family Hylidae
Genus Phyllomedusa
Species Phyllomedusa azurea
Ecozone Neotropic
Distribution Chacoan regions of eastern Bolivia (Beni and Santa Cruz provinces), Paraguay, northern Argentina (Salta, eastern Jujuy, Formosa, Chaco, northern Santiago del Estero, Santa Fe, and Corrients provinces) and pantanal and cerrado regions of central and western Brazil (Rondonia, Mato Grosso, Mato Grosso do Sul, Tocantins, Goias, Distrito Federal, Minas Gerais, and Sao Paulo) with an isolated population in Santa Catarina, southern Brazil
Antimicrobial & other activities antibacterial
Tissue Skin
Sequence MAFLKKSLFLVLFLGLVSLSICEEEKRETEEKENEQEDDDKSEEKRFLSLIPHAINAVSA
IAKHFG
Length 66
Signal peptide class Class-1
References:
1. for MIC/HC50 A.H. Thompson et al. / Peptides 28 (2007) 1331-1343. A combined mass spectrometric and cDNA sequencing approach to the isolation and characterization of novel antimicrobial peptides from the skin secretions of Phyllomedusa hypochondrialis azurea


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MAFLKKSLFLVLFLGLVSLSIC    
Prepro24 EEEKRETEEKENEQEDDDKSEEKR   
BioactivePhylloseptin-719YesFLSLIPHAINAVSAIAKHF 7.23.6