Brevinin-2R

Entry Brevinin-2R
Uniprot code P85095
Fasta P85095
Peptide names Brevinin-2R
Suborder Neobatrachia
Family Ranidae
Genus Rana
Species Pelophylax ridibundus
Ecozone Palearctic
Distribution Central Europe east of northeastern France, north to southern shore of Baltic Sea (and extreme southern Finland), south to extreme northeastern Spain, northern Italy and the Balkans including eastern Greece; east to ca. 81 degrees E in Asiatic Russia, south to western Iran and Afghanistan. Isolated populations in the high Asir region of of western Saudi Arabia, and oases of eastern Saudi Arabia; introduced into England and Italy
Antimicrobial & other activities anticancer
Tissue Skin
Sequence
Length 25
References:
2. for other activities S. Ghavami et al. / Journal of Cellular and Molecular Medicine 12 (2008) 1005-1022. Brevinin-2R(1) semi-selectively kills cancer cells by a distinct mechanism, which involves the lysosomal-mitochondrial death pathway


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
BioactiveBrevinin-2R25NoKLKNFAKGVAQSLLNKASCKLSGQC