Dermadistinctin-Q2

Entry Dermadistinctin-Q2
Uniprot code P83642
Fasta P83642
Peptide names Dermadistinctin-Q2
Suborder Neobatrachia
Family Hylidae
Genus Phyllomedusa
Species Phyllomedusa distincta
Ecozone Neotropic
Distribution Southeastern Brazil (Sao Paulo and Santa Catarina)
Antimicrobial & other activities antibacterial
Tissue Skin
Sequence
Length 25
References:
1. for MIC/HC50 C.V. Batista et al. / Peptides 20 (1999) 679-686. Antimicrobial peptides from the Brazilian frog Phyllomedusa distincta;  G.D. Brand et al. / Journal of Biological Chemistry 277 (2002) 49332-49340. Dermaseptins from Phyllomedusa oreades and Phyllomedusa distincta. Anti-Trypanosoma cruzi activity without cytotoxicity to mammalian cells;  L.P. Silva et al. / Comparative Biochemistry and Physiology, Part A 151 (2008) 329-335. Dermaseptins from Phyllomedusa oreades and Phyllomedusa distincta: liposomes fusion and/or lysis investigated by fluorescence and atomic force microscopy;  J.R.S.A. Leite et al. / Comparative Biochemistry and Physiology, Part A 151 (2008) 336-343. Dermaseptins from Phyllomedusa oreades and Phyllomedusa distincta: Secondary structure, antimicrobial activity, and mammalian cell toxicity


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
BioactiveDermadistinctin-Q225NoGLWSKIKEAAKTAGLMAMGFVNDMV 5.622