Citropin-1.1

Entry Citropin-1.1
Uniprot code P81835
Fasta P81835
Peptide names Citropin-1.1 Citropin-1.1.1 Citropin-1.1.2
Suborder Neobatrachia
Family Hylidae
Genus Litoria
Species Litoria citropa
Ecozone Australasia
Distribution Rocky streams in dense forest in the extreme east of Victoria and southeastern New South Wales and Victoria in southeastern Australia
Antimicrobial & other activities antibacterial, oxidative damage inhibitor, anticancer, antifungal, nNOS inhibitor
Tissue Skin
Sequence
Length 16
References:
1. for MIC/HC50 M.A. Apponyi et al. / Peptides 25 (2004) 1035-1054. Host-defence peptides of Australian anurans: structure, mechanism of action and evolutionary significance
2. for other activities R. Ghiselli et al. / Journal of Surgical Research 171 (2011) 726-733. Protective effect of citropin 1.1 and tazobactam-piperacillin against oxidative damage and lethality in mice models of gram-negative sepsis


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
BioactiveCitropin-1.116YesGLFDVIKKVASVIGGL  15.5
BioactiveCitropin-1.1.114NoFDVIKKVASVIGGL   
BioactiveCitropin-1.1.213NoDVIKKVASVIGGL