Dermaseptin DRG3

Entry Dermaseptin DRG3
Uniprot code P81488
Fasta P81488
Peptide names Dermaseptin DRG3
Suborder Neobatrachia
Family Hylidae
Genus Phyllomedusa
Species Phyllomedusa bicolor
Ecozone Neotropic
Distribution Amazon Basin in Brazil, Colombia, Bolivia, and Peru; the Guianan region of Venezuela and the Guianas. Possibly to be found in eastern Ecuador
Antimicrobial & other activities antibacterial
Tissue Skin
Sequence MAFLKKSLFLVLFLGLVSLSVCEEEKRENEDEEEQEDDEQSEEKRALWKTIIKGAGKMIG
SLAKNLLGSQAQPESEQ
Length 77
Signal peptide class Class-1
References:
1. for MIC/HC50 Y. Fleury et al. / Biochimica et Biophysica Acta 1396 (1998) 228-236. Synthesis, antimicrobial activity and gene structure of a novel member of the dermaseptin B family


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MAFLKKSLFLVLFLGLVSLSVC    
Prepro23 EEEKRENEDEEEQEDDEQSEEKR   
BioactiveDermaseptin DRG330NoALWKTIIKGAGKMIGSLAKNLLGSQAQPES 5050