Esculentin-1B

Entry Esculentin-1B
Uniprot code P40844
Fasta P40844
Peptide names Esculentin-1B Esculentin-1a/b
Suborder Neobatrachia
Family Ranidae
Genus Rana
Species Pelophylax esculentus
Ecozone Palearctic
Distribution Most of western, central and eastern Europe, Denmark and suthern most Sweden, Italy (river Po plain), up to 1550 m elevation. Introduced to United Kingdom and Spain.
Antimicrobial & other activities antibacterial
Tissue Skin
Sequence MFTLKKPLLLIVLLGMISLSLCEQERNADEEEGSEIKRGIFSKLAGKKLKNLLISGLKNV
GKEVGMDVVRTGIDIAGCKIKGEC
Length 84
Signal peptide class Class-1


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFTLKKPLLLIVLLGMISLSLC    
Prepro16 EQERNADEEEGSEIKR   
BioactiveEsculentin-1B46NoGIFSKLAGKKLKNLLISGLKNVGKEVGMDVVRTGIDIAGCKIKGEC