Esculentin-1A

Entry Esculentin-1A
Uniprot code P40843
Fasta P40843
Peptide names Esculentin-1A Esculentin-1P
Suborder Neobatrachia
Family Ranidae
Genus Rana
Species Pelophylax esculentus
Ecozone Palearctic
Distribution Most of western, central and eastern Europe, Denmark and suthern most Sweden, Italy (river Po plain), up to 1550 m elevation. Introduced to United Kingdom and Spain.
Antimicrobial & other activities antibacterial
Tissue Skin
Sequence
Length 46
References:
1. for MIC/HC50 T. Chen et al. / Genomics 87 (2006) 638-644. Cloning from tissue surrogates: Antimicrobial peptide (esculentin) cDNAs from the defensive skin secretions of Chinese ranid frogs


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
BioactiveEsculentin-1A46NoGIFSKLAGKKIKNLLISGLKNVGKEVGMDVVRTGIDIAGCKIKGEC 2.84.3