Esculentin-2MT1

Entry Esculentin-2MT1
Uniprot code E1AXF6
Fasta E1AXF6
Peptide names Esculentin-2MT1 Esculentin-2ALa Amolopin-9a
Suborder Neobatrachia
Family Ranidae
Genus Amolops
Species Amolops mantzorum
Ecozone Palearctic, Indomalaya
Distribution Southeastern Gansu, western Sichuan, and northwestern, central, and southwestern Yunnan, 900-2900 m elevation, China; presumably to be expected in adjacent northeastern Myanmar
Antimicrobial & other activities antibacterial
Tissue Skin
Sequence MFTMKKPLLLLFFLGTISLSLCEEERNADEDDGEKEVKRGIFALIKTAAKFVGKNLLKQA
GKAGLEHLACKANNQC
Length 76
Signal peptide class Class-1
References:
1. for MIC/HC50 M. Wang et al. / Comparative Biochemistry and Physiology, Part B 155 (2010) 72-76. Five novel antimicrobial peptides from skin secretions of the frog, Amolops loloensis


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFTMKKPLLLLFFLGTISLSLC    
Prepro17 EEERNADEDDGEKEVKR   
BioactiveEsculentin-2MT137NoGIFALIKTAAKFVGKNLLKQAGKAGLEHLACKANNQC 3.230.65