Ranatuerin-2-MG1

Entry Ranatuerin-2-MG1
Uniprot code E1AWD0
Fasta E1AWD0
Peptide names OGTI Ranatuerin-2SHb Ranatuerin-2R-RA2 Ranatuerin-2-MG1 Andersonin-W2
Suborder Neobatrachia
Family Ranidae
Genus Odorrana
Species Odorrana margaretae
Ecozone Palearctic, Indomalaya
Distribution Gansu, Guangxi, eastern Xizang, Sichuan, Hubei, Hunan, Guizhou, and southern Shaanxi, China, 390-1500 m elevation; mountains of northern Vientam (Lao Cai and Lai Chau provinces), 1900-2500 m
Antimicrobial & other activities antibacterial, serine protease inhibitor
Tissue Skin
Sequence MFTLKKSLLLLFFLGTISLSLCEEERDANEERRDDPDENEANEGEAKVEEIKRAVNIPFK
VHFRCKAAFC
Length 70
Signal peptide class Class-1
References:
1. for MIC/HC50 X. Yang et al. / Journal of Proteome Research 11 (2012) 306-319. Extremely Abundant Antimicrobial Peptides Existed in the Skins of Nine Kinds of Chinese Odorous Frogs
2. for other activities J. Li et al. / Biochimie 90 (2008) 1356-1361. A small trypsin inhibitor from the frog of Odorrana grahami


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFTLKKSLLLLFFLGTISLSLC    
Prepro31 EEERDANEERRDDPDENEANEGEAKVEEIKR   
BioactiveRanatuerin-2-MG117NoAVNIPFKVHFRCKAAFC 10.355.18