Bradykinin-4

Entry Bradykinin-4
Uniprot code D5MTI3
Fasta D5MTI3
Peptide names Bradykinin Bradykinin-4 [Thr6]-Bradykinin
Suborder Neobatrachia
Family Ranidae
Genus Rana
Species Rana tagoi okiensis
Ecozone Palearctic
Distribution Mountain regions of Honshu, Shikoku, and Kyushu Islands as well as Togoshima in the Oki Archipelago and Yakushima in the Tanegashima Group, Japan
Antimicrobial & other activities contraction of small intestine smooth muscle cells, relaxation of arterial smooth muscle cells
Tissue Skin, Brain
Sequence MFTLKKSLLLLFFLGTISLSLCEQERDADEDEYAGEAKAEDVKRAGYSRMIRRPPGFSPF
RIAPASTLKRDADEDEYAGEAKAEDVKRAGYSRMIRRPPGFSPFRIAPASTLKRDADEDE
YAGEAKAEDVKRAGYSRMIRRPPGFSPFRIAPASTLKRDADEDEYAGEAKAEDVKRAGYS
RMIRRPPGFTPFRIAPAIV
Length 199
Signal peptide class Class-1


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFTLKKSLLLLFFLGTISLSLC    
Prepro30 EQERDADEDEYAGEAKAEDVKRAGYSRMIR   
BioactiveBradykinin9NoRPPGFSPFR   
Prepro30 TLKRDADEDEYAGEAKAEDVKRAGYSRMIR   
BioactiveBradykinin9NoRPPGFSPFR   
Prepro30 TLKRDADEDEYAGEAKAEDVKRAGYSRMIR   
BioactiveBradykinin9NoRPPGFSPFR   
Prepro30 TLKRDADEDEYAGEAKAEDVKRAGYSRMIR   
Bioactive[Thr6]-Bradykinin9NoRPPGFTPFR