Ranatuerin-2TOb

Entry Ranatuerin-2TOb
Uniprot code D5MTH7
Fasta D5MTH7
Peptide names Ranatuerin-2TOb
Suborder Neobatrachia
Family Ranidae
Genus Rana
Species Rana tagoi okiensis
Ecozone Palearctic
Distribution Mountain regions of Honshu, Shikoku, and Kyushu Islands as well as Togoshima in the Oki Archipelago and Yakushima in the Tanegashima Group, Japan
Antimicrobial & other activities antibacterial, antifungal
Tissue Skin, Brain
Sequence MFTLKKSMLLLFFLGTISLSLCQEERGADEDDGGEMTEEVKRGLLNVIKDTAQNLFAAAL
EKLKCKVTKCN
Length 71
Signal peptide class Class-1
References:
1. for MIC/HC50 J.M. Conlon et al. / Toxicon 55 (2010) 430-435. Evidence from the primary structures of dermal antimicrobial peptides that Rana tagoi okiensis and Rana tagoi tagoi (Ranidae) are not conspecific subspecies


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFTLKKSMLLLFFLGTISLSLC    
Prepro20 QEERGADEDDGGEMTEEVKR   
BioactiveRanatuerin-2TOb29NoGLLNVIKDTAQNLFAAALEKLKCKVTKCN 80>160.00