Entry
Ranatuerin-2TOa
Uniprot code
D5MTH6
Fasta
D5MTH6
Peptide names
Ranatuerin-2TOa
Suborder
Neobatrachia
Family
Ranidae
Genus
Rana
Species
Rana tagoi okiensis
Ecozone
Palearctic
Distribution
Mountain regions of Honshu, Shikoku, and Kyushu Islands as well as Togoshima in the Oki Archipelago and Yakushima in the Tanegashima Group, Japan
Antimicrobial & other activities
antibacterial
Tissue
Skin, Brain
Sequence
MFTLKKSMLLLFFLGTISLSLCQEERGADEDDGGEMTEEVKRGLLNVIKDTAQNLFAAAL
Length
71
Signal peptide class
Class-1
References:
1. for MIC/HC50
J.M. Conlon et al. / Toxicon 55 (2010) 430-435. Evidence from the primary structures of dermal antimicrobial peptides that Rana tagoi okiensis and Rana tagoi tagoi (Ranidae) are not conspecific subspecies
Segment type
Name
Length
Amidated
Sequence
HC50 (μM)
MIC E. coli (μM)
MIC S. aureus (μM)
Signal
22
MFTLKKSMLLLFFLGTISLSLC
Prepro 20 QEERGADEDDGGEMTEEVKR Bioactive Ranatuerin-2TOa 29 No GLLNVIKDTAQNLFAAALDKLKCKVTKCN 80 >160.00