Brevinin-1TOa

Entry Brevinin-1TOa
Uniprot code D5MTH2
Fasta D5MTH2
Peptide names Brevinin-1TOa
Suborder Neobatrachia
Family Ranidae
Genus Rana
Species Rana tagoi okiensis
Ecozone Palearctic
Distribution Mountain regions of Honshu, Shikoku, and Kyushu Islands as well as Togoshima in the Oki Archipelago and Yakushima in the Tanegashima Group, Japan
Antimicrobial & other activities antibacterial, antifungal
Tissue Skin, Brain
Sequence MFTLKKSMLLLFFLGTISFSLCQEERDANEEEENGGEVKEEEKRGIGSILGVIAKGLPTL
ISWIKNRG
Length 68
Signal peptide class Class-1
References:
1. for MIC/HC50 J.M. Conlon et al. / Toxicon 55 (2010) 430-435. Evidence from the primary structures of dermal antimicrobial peptides that Rana tagoi okiensis and Rana tagoi tagoi (Ranidae) are not conspecific subspecies


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFTLKKSMLLLFFLGTISFSLC    
Prepro22 QEERDANEEEENGGEVKEEEKR   
BioactiveBrevinin-1TOa23YesGIGSILGVIAKGLPTLISWIKNR 205