Entry
Parkerin
Uniprot code
D0ES75
Fasta
D0ES75
Peptide names
Parkerin
Suborder
Neobatrachia
Family
Ranidae
Genus
Nanorana
Species
Nanorana parkeri
Ecozone
Palearctic, Indomalaya
Distribution
Southern third of Xizang (China) and high elevations of north-central Nepal; expected in Himalayan Bhutan, northeastern Kashmir, and India (Sikkim)
Antimicrobial & other activities
antibacterial, antioxidant, mast cell degranulation
Tissue
Skin
Sequence
MFTLKKSLFLVFFLGMVSLSLCRPESSAHAESSNDPTEEENAAGNEESVEKRGWANTLKN
Length
72
Signal peptide class
Class-1
References:
1. for MIC/HC50
Z. Lu et al. / Biochimie 92 (2010) 475-481. Novel families of antimicrobial peptides with multiple functions from skin of Xizang plateau frog, Nanorana parkeri
Segment type
Name
Length
Amidated
Sequence
HC50 (μM)
MIC E. coli (μM)
MIC S. aureus (μM)
Signal
22
MFTLKKSLFLVFFLGMVSLSLC
Prepro 30 RPESSAHAESSNDPTEEENAAGNEESVEKR Bioactive Parkerin 20 No GWANTLKNVAGGLCKITGAA >51.40 19.28