Japonicin-1NPa

Entry Japonicin-1NPa
Uniprot code D0ES73
Fasta D0ES73
Peptide names Japonicin-1NPa
Suborder Neobatrachia
Family Ranidae
Genus Nanorana
Species Nanorana parkeri
Ecozone Palearctic, Indomalaya
Distribution Southern third of Xizang (China) and high elevations of north-central Nepal; expected in Himalayan Bhutan, northeastern Kashmir, and India (Sikkim)
Antimicrobial & other activities antibacterial, antioxidant, mast cell degranulation
Tissue Skin
Sequence MFTLKKTLFLVFFLGMVSLSLCEQERHAHEETSNDPTEEENAAGNEESGEEGDMEKRFLL
FPLMCKIQGKC
Length 71
Signal peptide class Class-1
References:
1. for MIC/HC50 Z. Lu et al. / Biochimie 92 (2010) 475-481. Novel families of antimicrobial peptides with multiple functions from skin of Xizang plateau frog, Nanorana parkeri


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFTLKKTLFLVFFLGMVSLSLC    
Prepro35 EQERHAHEETSNDPTEEENAAGNEESGEEGDMEKR   
BioactiveJaponicin-1NPa14NoFLLFPLMCKIQGKC >61.0022.85