Lividin-5

Entry Lividin-5
Uniprot code C3RSZ6
Fasta C3RSZ6
Peptide names Lividin-5 Ranacyclin-B-RL1
Suborder Neobatrachia
Family Ranidae
Genus Odorrana
Species Odorrana livida
Ecozone Indomalaya
Distribution Known definitely only from the type locality (Myanmar) near the Thai border, although animals have been referred, apparently in error, to this taxon, from northeastern India to southern China
Antimicrobial & other activities antibacterial, antifungal, trypsin inhibitor
Tissue Skin
Sequence MFTMKKSLLFLFFLGIVSLSFCEQERDADEEDGGRVTEEEVKRAALRGCWTKSIPPKPCP
GKR
Length 63
Signal peptide class Class-1
References:
1. for MIC/HC50 X. Yan et al. / Amino Acids (2011) DOI 10.1007/s00726-011-1079-8. Bi-functional peptides with both trypsin-inhibitory and antimicrobial activities are frequent defensivemolecules in Ranidae amphibian skins


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFTMKKSLLFLFFLGIVSLSFC    
Prepro21 EQERDADEEDGGRVTEEEVKR   
BioactiveLividin-520NoAALRGCWTKSIPPKPCPGKR 46.25.8