Maximin 63/H39

Entry Maximin 63/H39
Uniprot code C3RSW2
Fasta C3RSW2
Peptide names Maximin 63 Maximin H39 Maximin 63/H39
Suborder Archeobatrachia
Family Bombinatoridae
Genus Bombina
Species Bombina maxima
Ecozone Palearctic, Indomalaya
Distribution Yunnan, southwestern Sichuan, Hubei, Guizhou, and northern Guangxi, China; adjacent northern Vietnam
Antimicrobial & other activities antibacterial; Maximin H39: antibacterial, antifungal
Tissue Skin, Brain
Sequence MNFKYIVAVSFLIASAYARSVQNDEQSLSQRDVLEEESLREIRGIGGVLLGAGKATLKGL
AKVLAEKYANGKRTAEDHEVMKRLEAVMRDPDSLDHPEEASERETRGFNQDEIAKEKRIL
GPVLGLVGNALGGLIKKLANYNQ
Length 143
Signal peptide class Class-3
References:
1. for MIC/HC50 R. Liu et al. / Journal of Proteome Research 10 (2011) 1806-1815. There are abundant antimicrobial peptides in brains of two kinds of Bombina toads


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   18   MNFKYIVAVSFLIASAYA    
Prepro25 RSVQNDEQSLSQRDVLEEESLREIR   
BioactiveMaximin 6327YesGIGGVLLGAGKATLKGLAKVLAEKYAN100 7.2
Prepro48 GKRTAEDHEVMKRLEAVMRDPDSLDHPEEASERETRGFNQDEIAKEKR   
BioactiveMaximin H3920YesILGPVLGLVGNALGGLIKKL60 4.8