Antimicrobial peptide

Entry Antimicrobial peptide
Uniprot code C3RSU2
Fasta C3RSU2
Peptide names Antimicrobial peptide Maximin H1
Suborder Archeobatrachia
Family Bombinatoridae
Genus Bombina
Species Bombina maxima
Ecozone Palearctic, Indomalaya
Distribution Yunnan, southwestern Sichuan, Hubei, Guizhou, and northern Guangxi, China; adjacent northern Vietnam
Antimicrobial & other activities antibacterial; Maximin H1: antibacterial, antifungal
Tissue Skin
Sequence MNFKYIVAVSFLIASAYARSEENDEQSLSQRDVLEEESLREIRGIGTKIIGGLKTAVKGA
LKELAFTYVNGKRTAEDHEVMKRLEAVMRDLDSLDYPEEAFERETRGFNQEEVANLFTKK
EKRILGPVISTIGGVLGGLLKNLG
Length 144
Signal peptide class Class-3
References:
1. for MIC/HC50 R. Lai et al. / Peptides 23 (2002) 427-435. Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   18   MNFKYIVAVSFLIASAYA    
Prepro25 RSEENDEQSLSQRDVLEEESLREIR   
BioactiveAntimicrobial peptide27NoGIGTKIIGGLKTAVKGALKELAFTYVN   
Prepro53 GKRTAEDHEVMKRLEAVMRDLDSLDYPEEAFERETRGFNQEEVANLFTKKEKR   
BioactiveMaximin H120YesILGPVISTIGGVLGGLLKNL 4.662.33