Antimicrobial peptide

Entry Antimicrobial peptide
Uniprot code C3RSS8
Fasta C3RSS8
Peptide names Antimicrobial peptide Maximin H3
Suborder Archeobatrachia
Family Bombinatoridae
Genus Bombina
Species Bombina maxima
Ecozone Palearctic, Indomalaya
Distribution Yunnan, southwestern Sichuan, Hubei, Guizhou, and northern Guangxi, China; adjacent northern Vietnam
Antimicrobial & other activities antibacterial; Maximin H3: antibacterial, antifungal
Tissue Skin
Sequence MNFKYIVAVSFLIASAYARSVQNDEQSLSRRDVLEEESLREIRGIGGKILGGLKTVLKDA
AKELAATYLHRKRTAEEHEVMKRLEAVMRDLDSLDHPEEASERETRGFNQDEIANLFTKK
EKRILGPVLGLVGNALGGLIKKIG
Length 144
Signal peptide class Class-3
References:
1. for MIC/HC50 R. Lai et al. / Peptides 23 (2002) 427-435. Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   18   MNFKYIVAVSFLIASAYA    
Prepro25 RSVQNDEQSLSRRDVLEEESLREIR   
BioactiveAntimicrobial peptide27NoGIGGKILGGLKTVLKDAAKELAATYLH   
Prepro53 RKRTAEEHEVMKRLEAVMRDLDSLDHPEEASERETRGFNQDEIANLFTKKEKR   
BioactiveMaximin H320YesILGPVLGLVGNALGGLIKKI 10.295.15