Maximin 28/H23

Entry Maximin 28/H23
Uniprot code C3RSQ3
Fasta C3RSQ3
Peptide names Maximin 28 Maximin H23 Maximin 28/H23
Suborder Archeobatrachia
Family Bombinatoridae
Genus Bombina
Species Bombina maxima
Ecozone Palearctic, Indomalaya
Distribution Yunnan, southwestern Sichuan, Hubei, Guizhou, and northern Guangxi, China; adjacent northern Vietnam
Antimicrobial & other activities antibacterial, antifungal
Tissue Skin, Brain
Sequence MNFKYIVAVSFLIASAYARSEENDEQSLSQRDVLEEESLREIRGIGTKFLGGVKTALKGA
LKELASTYVNGKRTAEDHEVMKRLEAVMRDLDSLDYPEEAAERETRGFNEEEIANLFTKK
EKRILGPVISTIGNVLGGLLKNLG
Length 144
Signal peptide class Class-3
References:
1. for MIC/HC50 R. Liu et al. / Journal of Proteome Research 10 (2011) 1806-1815. There are abundant antimicrobial peptides in brains of two kinds of Bombina toads


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   18   MNFKYIVAVSFLIASAYA    
Prepro25 RSEENDEQSLSQRDVLEEESLREIR   
BioactiveMaximin 2827YesGIGTKFLGGVKTALKGALKELASTYVN1003.431.72
Prepro53 GKRTAEDHEVMKRLEAVMRDLDSLDYPEEAAERETRGFNEEEIANLFTKKEKR   
BioactiveMaximin H2320YesILGPVISTIGNVLGGLLKNL