Ranatuerin-4

Entry Ranatuerin-4
Uniprot code C1C3U1
Fasta C1C3U1
Peptide names Ranatuerin-4
Suborder Neobatrachia
Family Ranidae
Genus Lithobates
Species Lithobates catesbeianus
Ecozone Nearctic, Neotropic
Distribution Eastern North America, except southern Florida, north to Nova Scotia, New Brunswick, southern Quebec, and southern Ontario (Canada), west to the central plains and south to Hidalgo, Puebla, and adjacent Veracruz (Mexico); introduced on Cuba, Isla de Juventud (= Isla de Pinos), Puerto Rico, Hispaniola, and Jamaica in the Antilles; introduced widely in the rest of the world including the Netherlands, Bordeaux region of France, Belgium, northern Italy, western Spain, Crete, Malaya (Malaysia), Java, Bali, Japan, southern and western Mexico, northern Thailand, Korea, and Taiwan (China)
Antimicrobial & other activities antibacterial
Tissue Skin
Sequence MFTSKKSLLLLFFLGTINLSFCEEERDAEEERRDNPDERDVEVEKRFLPFIARLAAKVFP
SIICSVTKKC
Length 70
Signal peptide class Class-1
References:
1. for MIC/HC50 J. Goraya et al. / Biochemical and Biophysical Research Communications 250 (1998) 589-592. Ranatuerins: antimicrobial peptides isolated from the skin of the American bullfrog, Rana catesbeiana


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFTSKKSLLLLFFLGTINLSFC    
Prepro24 EEERDAEEERRDNPDERDVEVEKR   
BioactiveRanatuerin-424NoFLPFIARLAAKVFPSIICSVTKKC  55