Rugosin-RN

Entry Rugosin-RN
Uniprot code C0ILC6
Fasta C0ILC6
Peptide names Rugosin-RN Rugosin-RN1
Suborder Neobatrachia
Family Ranidae
Genus Hylarana
Species Hylarana nigrovittata
Ecozone Indomalaya
Distribution Nepal and West Bengal, Assam. and Meghalaya (India) as well as adjacent Bangladesh to Yunnan and Guangxi (China), Vietnam and south to Malaya
Antimicrobial & other activities antibacterial, antifungal, mast cell degranulation
Tissue Skin
Sequence MFTMKKSLLFLFFLGTISLSFREEERSADEDDEGEMTEEEKRSIRDKIKTIAIDLAKSAG
TGVLKTLICKLDKSC
Length 75
Signal peptide class Class-1
References:
1. for MIC/HC50 Y. Ma et al. / Genomics 95 (2010) 66-71. Peptidomics and genomics analysis of novel antimicrobial peptides from the frog, Rana nigrovittata


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFTMKKSLLFLFFLGTISLSFR    
Prepro20 EEERSADEDDEGEMTEEEKR   
BioactiveRugosin-RN33NoSIRDKIKTIAIDLAKSAGTGVLKTLICKLDKSC 7.141.34