Nigroain-B

Entry Nigroain-B
Uniprot code C0IL72
Fasta C0IL72
Peptide names Nigroain-B Nigroain-B1
Suborder Neobatrachia
Family Ranidae
Genus Hylarana
Species Hylarana nigrovittata
Ecozone Indomalaya
Distribution Nepal and West Bengal, Assam. and Meghalaya (India) as well as adjacent Bangladesh to Yunnan and Guangxi (China), Vietnam and south to Malaya
Antimicrobial & other activities antibacterial, mast cell degranulation, histamine releasing
Tissue Skin
Sequence MFTMKKSLLLLFFLGTISLSLCEEERDADEEDGGEATEQEERDVQRRCVISAGWNHKIRC
KLTGNC
Length 66
Signal peptide class Class-1
References:
1. for MIC/HC50 Y. Ma et al. / Genomics 95 (2010) 66-71. Peptidomics and genomics analysis of novel antimicrobial peptides from the frog, Rana nigrovittata


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFTMKKSLLLLFFLGTISLSLC    
Prepro25 EEERDADEEDGGEATEQEERDVQRR   
BioactiveNigroain-B19NoCVISAGWNHKIRCKLTGNC  23.77