Preprofallaxidin-2

Entry Preprofallaxidin-2
Uniprot code B5LUQ3
Fasta B5LUQ3
Peptide names Fallaxidin-3.1 Fallaxidin-3.2 Preprofallaxidin-2 Preprofallaxidin-6 Preprofallaxidin-8 Preprofallaxidin-9
Suborder Neobatrachia
Family Hylidae
Genus Litoria
Species Litoria fallax
Ecozone Australasia
Distribution Coastal southwestern Queensland into northeastern New South Wales, Australia; introduced on Guam
Antimicrobial & other activities antibacterial
Tissue Skin
Sequence MASLKKSLFLVLFLGLVSLSICEKEKRENEGNENEEEEENHEEGSEEKRGLLDLAKHVIG
IASKLGKRSEEKRGLLDFAKHVIGIASKLGK
Length 91
Signal peptide class Class-1
References:
2. for other activities R.J. Jackway et al. / Rapid Communications in Mass Spectrometry 22 (2008) 3207-3216. The fallaxidin peptides from the skin secretion of the eastern dwarf tree frog Litoria fallax. Sequence determination by positive and negative ion electrospray mass spectrometry: antimicrobial activity and cDNA cloning of the fallaxidins


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MASLKKSLFLVLFLGLVSLSIC    
Prepro27 EKEKRENEGNENEEEEENHEEGSEEKR   
BioactiveFallaxidin-3.116YesGLLDLAKHVIGIASKL   
Prepro8 GKRSEEKR   
BioactiveFallaxidin-3.216YesGLLDFAKHVIGIASKL