Maximin 21/H1

Entry Maximin 21/H1
Uniprot code B5L161
Fasta B5L161
Peptide names Maximin 21 Maximin 21/H1 Maximin H1
Suborder Archeobatrachia
Family Bombinatoridae
Genus Bombina
Species Bombina maxima
Ecozone Palearctic, Indomalaya
Distribution Yunnan, southwestern Sichuan, Hubei, Guizhou, and northern Guangxi, China; adjacent northern Vietnam
Antimicrobial & other activities antibacterial; Maximin H1: antibacterial, antifungal
Tissue Skin
Sequence MNFKYIVAVSFLIASAYARSEENDEQTLSQRDVLEEESLREIRGIGTKIIGGLKTAVKGA
LKELASTYVNGKRTAEDHEVMKRLEAVMRDLDSLDYPEEASERETRGFNQEEIANLFTKK
EKRILGPVISTIGGVLGGLLKNLG
Length 144
Signal peptide class Class-3
References:
1. for MIC/HC50 R. Lai et al. / Peptides 23 (2002) 427-435. Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   18   MNFKYIVAVSFLIASAYA    
Prepro25 RSEENDEQTLSQRDVLEEESLREIR   
BioactiveMaximin 2127NoGIGTKIIGGLKTAVKGALKELASTYVN   
Prepro53 GKRTAEDHEVMKRLEAVMRDLDSLDYPEEASERETRGFNQEEIANLFTKKEKR   
BioactiveMaximin H120YesILGPVISTIGGVLGGLLKNL 4.662.33