Maximin 22/H1

Entry Maximin 22/H1
Uniprot code B5L141
Fasta B5L141
Peptide names Maximin 22 Maximin 22/H1 Maximin H1
Suborder Archeobatrachia
Family Bombinatoridae
Genus Bombina
Species Bombina maxima
Ecozone Palearctic, Indomalaya
Distribution Yunnan, southwestern Sichuan, Hubei, Guizhou, and northern Guangxi, China; adjacent northern Vietnam
Antimicrobial & other activities antibacterial; Maximin H1: antibacterial, antifungal
Tissue Skin
Sequence MNFKYIVAVSFLIASAYARSEENDEQSLSQRDVLEEESLREIRGIGTKIIGGLKTAVKGA
LKELVFTYVNGKRTAEDHEVMKRLEAVMRDLDSLDYPEEVFERETRGFNQEEIANLFTKK
EKRILGPVISTIGGVLGGLLKNLG
Length 144
Signal peptide class Class-3
References:
1. for MIC/HC50 R. Lai et al. / Peptides 23 (2002) 427-435. Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   18   MNFKYIVAVSFLIASAYA    
Prepro25 RSEENDEQSLSQRDVLEEESLREIR   
BioactiveMaximin 2227NoGIGTKIIGGLKTAVKGALKELVFTYVN   
Prepro53 GKRTAEDHEVMKRLEAVMRDLDSLDYPEEVFERETRGFNQEEIANLFTKKEKR   
BioactiveMaximin H120YesILGPVISTIGGVLGGLLKNL 4.662.33