Maximin 4/H19

Entry Maximin 4/H19
Uniprot code B5L130
Fasta B5L130
Peptide names Maximin H19 Maximin 4/H19 Maximin 4
Suborder Archeobatrachia
Family Bombinatoridae
Genus Bombina
Species Bombina maxima
Ecozone Palearctic, Indomalaya
Distribution Yunnan, southwestern Sichuan, Hubei, Guizhou, and northern Guangxi, China; adjacent northern Vietnam
Antimicrobial & other activities antibacterial, antifungal, anticancer
Tissue Skin
Sequence MNFKYIVAVSFLIASAYARSVQNDEQFLSQRDVLEEESLREIRGIGGVLLSAGKAALKGL
AKVLAEKYANGKRTAEDHEVMKRLEAIMRDLDSLDHPEEAFERETRGFNQDEIAKEKRIL
GPVLGLVGNPLGGLIKKIG
Length 139
Signal peptide class Class-3
References:
1. for MIC/HC50 R. Lai et al. / Peptides 23 (2002) 427-435. Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   18   MNFKYIVAVSFLIASAYA    
Prepro25 RSVQNDEQFLSQRDVLEEESLREIR   
BioactiveMaximin 427YesGIGGVLLSAGKAALKGLAKVLAEKYAN 1.031.03
Prepro48 GKRTAEDHEVMKRLEAIMRDLDSLDHPEEAFERETRGFNQDEIAKEKR   
BioactiveMaximin H1920NoILGPVLGLVGNPLGGLIKKI