Maximin 24/H3

Entry Maximin 24/H3
Uniprot code B5L118
Fasta B5L118
Peptide names Maximin 24 Maximin 24/H3 Maximin H3
Suborder Archeobatrachia
Family Bombinatoridae
Genus Bombina
Species Bombina maxima
Ecozone Palearctic, Indomalaya
Distribution Yunnan, southwestern Sichuan, Hubei, Guizhou, and northern Guangxi, China; adjacent northern Vietnam
Antimicrobial & other activities antibacterial; Maximin H3: antibacterial, antifungal
Tissue Skin
Sequence MNFKYIVAVSFLIASAYARSVKNDEQSLSQRDVLEEESLREIRGIGRKFLGGVKTTFRCG
DKDFASKHLYGKRTAEEHEVMKRLEAIMRDLDSLDHPEEASERETRGFNQDEIANLFTKK
EKRILGPVLGLVGNALGGLIKKIG
Length 144
Signal peptide class Class-3
References:
1. for MIC/HC50 R. Lai et al. / Peptides 23 (2002) 427-435. Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   18   MNFKYIVAVSFLIASAYA    
Prepro25 RSVKNDEQSLSQRDVLEEESLREIR   
BioactiveMaximin 2427NoGIGRKFLGGVKTTFRCGDKDFASKHLY   
Prepro53 GKRTAEEHEVMKRLEAIMRDLDSLDHPEEASERETRGFNQDEIANLFTKKEKR   
BioactiveMaximin H320YesILGPVLGLVGNALGGLIKKI 10.295.15