Brevinin-1PLb

Entry Brevinin-1PLb
Uniprot code A7WNV3
Fasta A7WNV3
Peptide names Brevinin-1Vb Brevinin-1PLb
Suborder Neobatrachia
Family Ranidae
Genus Lithobates
Species Lithobates palustris
Ecozone Palearctic
Distribution Eastern North America, from southern Quebec through southern Ontario (Canada) south through extreme eastern Minnesota and on to East Texas then east to South Carolina (USA), extreme western Florida, and north to Nova Scotia (Canada)
Antimicrobial & other activities antibacterial, antifungal
Tissue Skin
Sequence MFTTKKSMLLLFFLGTINLSLCEEERNAEEERRDEPDEMNVEVEKRFLPLIAGLAANFLP
KIFCAITKKC
Length 70
Signal peptide class Class-1
References:
1. for MIC/HC50 Y.J. Basir et al. / Biochimica et Biophysica Acta 1543 (2000) 95-105. Multiple antimicrobial peptides and peptides related to bradykinin and neuromedin N isolated from skin secretions of the pickerel frog, Rana palustris


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFTTKKSMLLLFFLGTINLSLC    
Prepro24 EEERNAEEERRDEPDEMNVEVEKR   
BioactiveBrevinin-1PLb24NoFLPLIAGLAANFLPKIFCAITKKC 269