Odorranain-H1

Entry Odorranain-H1
Uniprot code A6MBM0
Fasta A6MBM0
Peptide names Odorranain-H1 Nigrocin-2GRb
Suborder Neobatrachia
Family Ranidae
Genus Odorrana
Species Odorrana grahami
Ecozone Palearctic, Indomalaya
Distribution Sichuan, Guizhou, and central and western Yunnan, China; a distantly alloparic population present in southern Shanxi, China: presumably to be found in eastern Myanmar along the Yunna, China, border; reported in Lao Cai and Lai Chau provinces, Vietnam, 1150-3200 m elevation
Antimicrobial & other activities antibacterial, antifungal, mast cell degranulation, nitric oxide releasing, histamine releasing
Tissue Skin
Sequence MFTLKKSLLLLFFLGTINLSLCQDETNAEEERRDEEVAKMEEIKRGLFGKILGVGKKVLC
GLSGMC
Length 66
Signal peptide class Class-1
References:
1. for MIC/HC50 J.M. Conlon et al. / Peptides 27 (2006) 2111-2117. Antimicrobial peptides from diverse families isolated from the skin of the Asian frog, Rana grahami
2. for other activities J. Li et al. / Molecular & Cellular Proteomics 6 (2007) 882-894. Anti-infection Peptidomics of Amphibian Skin


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFTLKKSLLLLFFLGTINLSLC    
Prepro23 QDETNAEEERRDEEVAKMEEIKR   
BioactiveOdorranain-H121NoGLFGKILGVGKKVLCGLSGMC40312.5