Entry
Odorranain-C7
Uniprot code
A6MBE6
Fasta
A6MBE6
Peptide names
Odorranain-C7 Odorranain-C8 Brevinin-2GRb
Suborder
Neobatrachia
Family
Ranidae
Genus
Odorrana
Species
Odorrana grahami
Ecozone
Palearctic, Indomalaya
Distribution
Sichuan, Guizhou, and central and western Yunnan, China; a distantly alloparic population present in southern Shanxi, China: presumably to be found in eastern Myanmar along the Yunna, China, border; reported in Lao Cai and Lai Chau provinces, Vietnam, 1150-3200 m elevation
Antimicrobial & other activities
antibacterial, antifungal, mast cell degranulation, histamine releasing
Tissue
Skin
Sequence
MFTMKKSLLLLLFLGTISLSLCEEERDADEEEGEMTEEEVKRGVLGTVKNLLIGAGKSAA
Length
75
Signal peptide class
Class-1
References:
1. for MIC/HC50
J.M. Conlon et al. / Peptides 27 (2006) 2111-2117. Antimicrobial peptides from diverse families isolated from the skin of the Asian frog, Rana grahami
2. for other activities
J. Li et al. / Molecular & Cellular Proteomics 6 (2007) 882-894. Anti-infection Peptidomics of Amphibian Skin
Segment type
Name
Length
Amidated
Sequence
HC50 (μM)
MIC E. coli (μM)
MIC S. aureus (μM)
Signal
22
MFTMKKSLLLLLFLGTISLSLC
Prepro 20 EEERDADEEEGEMTEEEVKR Bioactive Odorranain-C7 33 No GVLGTVKNLLIGAGKSAAQSVLKTLSCKLSNDC 180 6 25