Entry
Nigrosin-OG20
Uniprot code
A6MB66
Fasta
A6MB66
Peptide names
Grahamin-1 Nigrosin-MG2 Nigrosin-OG17 Nigrosin-OG20
Suborder
Neobatrachia
Family
Ranidae
Genus
Odorrana
Species
Odorrana grahami
Ecozone
Palearctic, Indomalaya
Distribution
Sichuan, Guizhou, and central and western Yunnan, China; a distantly alloparic population present in southern Shanxi, China: presumably to be found in eastern Myanmar along the Yunna, China, border; reported in Lao Cai and Lai Chau provinces, Vietnam, 1150-3200 m elevation
Antimicrobial & other activities
antibacterial, antifungal
Tissue
Skin
Sequence
MFTLKKSLLLLFFLGTINLSLCQDETNAEEERRDEEVAKMEEIKRGLLSGILGAGKNIVC
Length
66
Signal peptide class
Class-1
References:
1. for MIC/HC50
X. Xu et al. / Toxicon 47 (2006) 459-464. Two antimicrobial peptides from skin secretions of Rana grahami
2. for other activities
J. Li et al. / Molecular & Cellular Proteomics 6 (2007) 882-894. Anti-infection Peptidomics of Amphibian Skin
Segment type
Name
Length
Amidated
Sequence
HC50 (μM)
MIC E. coli (μM)
MIC S. aureus (μM)
Signal
22
MFTLKKSLLLLFFLGTINLSLC
Prepro 23 QDETNAEEERRDEEVAKMEEIKR Bioactive Nigrosin-OG20 21 No GLLSGILGAGKNIVCGLSGLC 3.86 1.29