Nigrosin-OG2

Entry Nigrosin-OG2
Uniprot code A6MB02
Fasta A6MB02
Peptide names Nigrosin-OG2
Suborder Neobatrachia
Family Ranidae
Genus Odorrana
Species Odorrana grahami
Ecozone Palearctic, Indomalaya
Distribution Sichuan, Guizhou, and central and western Yunnan, China; a distantly alloparic population present in southern Shanxi, China: presumably to be found in eastern Myanmar along the Yunna, China, border; reported in Lao Cai and Lai Chau provinces, Vietnam, 1150-3200 m elevation
Antimicrobial & other activities mast cell degranulation, nitric oxide releasing, histamine releasing
Tissue Skin
Sequence MFTLKKSLLLLLFLGTINLSFCQDETNAPVERRDEEVAKMEEIKRGLLGKILGVEKKVLC
GLSGMC
Length 66
Signal peptide class Class-1
References:
2. for other activities J. Li et al. / Molecular & Cellular Proteomics 6 (2007) 882-894. Anti-infection Peptidomics of Amphibian Skin


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFTLKKSLLLLLFLGTINLSFC    
Prepro23 QDETNAPVERRDEEVAKMEEIKR   
BioactiveNigrosin-OG221NoGLLGKILGVEKKVLCGLSGMC