Esculentin-2-OG10

Entry Esculentin-2-OG10
Uniprot code A6MAW7
Fasta A6MAW7
Peptide names Esculentin-2-OG10 Esculentin-2-OG7 Brevinin-2GRc Esculentin-2-OA3
Suborder Neobatrachia
Family Ranidae
Genus Odorrana
Species Odorrana grahami
Ecozone Palearctic, Indomalaya
Distribution Sichuan, Guizhou, and central and western Yunnan, China; a distantly alloparic population present in southern Shanxi, China: presumably to be found in eastern Myanmar along the Yunna, China, border; reported in Lao Cai and Lai Chau provinces, Vietnam, 1150-3200 m elevation
Antimicrobial & other activities antibacterial
Tissue Skin
Sequence MFTMKKSLLVLFFLGTTSLSLCQEERAADEEDNGEVGEVKRGLFTLIKGAAKLIGKTVAK
EAGKTGLELMACKITNQC
Length 78
Signal peptide class Class-1
References:
1. for MIC/HC50 J.M. Conlon et al. / Peptides 27 (2006) 2111-2117. Antimicrobial peptides from diverse families isolated from the skin of the Asian frog, Rana grahami


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFTMKKSLLVLFFLGTTSLSLC    
Prepro19 QEERAADEEDNGEVGEVKR   
BioactiveEsculentin-2-OG1037NoGLFTLIKGAAKLIGKTVAKEAGKTGLELMACKITNQC10012.550