Esculentin-1-OG5

Entry Esculentin-1-OG5
Uniprot code A6MAW0
Fasta A6MAW0
Peptide names Esculentin-1-OG5 Esculentin-1-RA8 Esculentin-1-OA3
Suborder Neobatrachia
Family Ranidae
Genus Odorrana
Species Odorrana grahami
Ecozone Palearctic, Indomalaya
Distribution Sichuan, Guizhou, and central and western Yunnan, China; a distantly alloparic population present in southern Shanxi, China: presumably to be found in eastern Myanmar along the Yunna, China, border; reported in Lao Cai and Lai Chau provinces, Vietnam, 1150-3200 m elevation
Antimicrobial & other activities antibacterial, antifungal
Tissue Skin
Sequence MFSLKKSLLLIVLLGIISLSLCEQERAADEDEGSEIKRGLFSKFAGKGIKDLIFKGVKHI
GKEVGMDVIRTGIDVAGCKIKGEC
Length 84
Signal peptide class Class-1
References:
1. for MIC/HC50 X. Yang et al. / Journal of Proteome Research 11 (2012) 306-319. Extremely Abundant Antimicrobial Peptides Existed in the Skins of Nine Kinds of Chinese Odorous Frogs


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFSLKKSLLLIVLLGIISLSLC    
Prepro16 EQERAADEDEGSEIKR   
BioactiveEsculentin-1-OG546NoGLFSKFAGKGIKDLIFKGVKHIGKEVGMDVIRTGIDVAGCKIKGEC 1.111.11