Esculentin-1-OG2

Entry Esculentin-1-OG2
Uniprot code A6MAV8
Fasta A6MAV8
Peptide names Esculentin-1-MG2 Esculentin-1-OG2 Esculentin-1-RA5 Esculentin-1-OA5
Suborder Neobatrachia
Family Ranidae
Genus Odorrana
Species Odorrana grahami
Ecozone Palearctic, Indomalaya
Distribution Sichuan, Guizhou, and central and western Yunnan, China; a distantly alloparic population present in southern Shanxi, China: presumably to be found in eastern Myanmar along the Yunna, China, border; reported in Lao Cai and Lai Chau provinces, Vietnam, 1150-3200 m elevation
Antimicrobial & other activities antibacterial, antifungal
Tissue Skin
Sequence MFTLKKPLLLIVLLGIISLSLCEQERAADEDEGSEIKRGLFSKFAGKGIKNFLIKGVKHI
GKEVGMDVIRTGIDVAGCKIKGEC
Length 84
Signal peptide class Class-1
References:
1. for MIC/HC50 X. Yang et al. / Journal of Proteome Research 11 (2012) 306-319. Extremely Abundant Antimicrobial Peptides Existed in the Skins of Nine Kinds of Chinese Odorous Frogs


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFTLKKPLLLIVLLGIISLSLC    
Prepro16 EQERAADEDEGSEIKR   
BioactiveEsculentin-1-OG246NoGLFSKFAGKGIKNFLIKGVKHIGKEVGMDVIRTGIDVAGCKIKGEC 0.70.35