Amolopin-2a

Entry Amolopin-2a
Uniprot code A0SN45
Fasta A0SN45
Peptide names Amolopin-2a Temporin-ALa Temporin-MT3
Suborder Neobatrachia
Family Ranidae
Genus Amolops
Species Amolops loloensis
Ecozone Palearctic
Distribution High-gradients streams in Zhaojue, Mianning, Hongya, Luding, and Baoxing in southern Sichuan, China, 1840-3700 m elevation
Antimicrobial & other activities antibacterial, antifungal, mast cell degranulation, histamine releasing
Tissue Skin
Sequence MFTLKKSLLLLFFLGTINLSLCEQERNAEEERRDEPDERNAEVEKRFLPIVGKLLSGLSG
LLGK
Length 64
Signal peptide class Class-1
References:
1. for MIC/HC50 Yi Lu et al. / Peptides 27 (2006) 3085-3091. Two families of antimicrobial peptides with multiple functions from skin of rufous-spotted torrent frog, Amolops loloensis


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFTLKKSLLLLFFLGTINLSLC    
Prepro24 EQERNAEEERRDEPDERNAEVEKR   
BioactiveAmolopin-2a16YesFLPIVGKLLSGLSGLL 1.841.23